Table 2 Synergy analysis for dasatinib and curcumin combination therapy in chemo-resistant colon cancer cells
From: Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells
COMBINATION THERAPY | COMBINATION INDEX (CI) | ||
|---|---|---|---|
Dasatinib (μM) | Curcumin (μM) | CR HCT-116 (p53 wt) | CR HT-29 (p53 mutant) |
0.25 | 2.5 | 0.42 | 0.16 |
0.5 | 5.0 | 0.43 | 0.28 |
1.0 | 10.0 | 0.61 | 0.46 |
2.0 | 20.0 | 0.72 | 0.76 |
4.0 | 40.0 | 0.95 | 0.89 |