Figure 7From: Membrane estrogen receptor-α-mediated nongenomic actions of phytoestrogens in GH3/B6/F10 pituitary tumor cells Involvement of mERα in nongenomic effects by phytoestrogens. Comparison of mERα-depleted subclone D9 (open bars) with mERα-enriched subclone F10 cells (solid bars) treated with different estrogens: estradiol (E2), coumesterol (Cou), daidzein (Dai), genistein (Gen), and trans-resveratrol (Res). (A) PRL released, (B) ERK activation, (C) JNK activation, and (D) % of cells showing Ca2+ influx. * = p < 0.05 compared to vehicle-treated cells (Con).Back to article page