Figure 6From: Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration* Effect of SHP-1 knockdown on migration. HUVEC were transfected with scrambled control or SHP-1 siRNA using oligofectamine. After 48 h, the cells were plated on 6 well plates and wound healing migration carried out as described in Materials and Methods. Data represent average of three independent determinations each in triplicate.Back to article page