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Figure 5 | Journal of Molecular Signaling

Figure 5

From: The α1D-adrenergic receptor is expressed intracellularly and coupled to increases in intracellular calcium and reactive oxygen species in human aortic smooth muscle cells

Figure 5

Effect of Phenylephrine on the Levels of Reactive Oxygen Species Levels in Human Aortic Smooth Muscle Cells. Human aortic smooth muscle cells were loaded with Mitotracker ROS for 20 min. The ability of 10 uM phenylephrine to increase the levels of reactive oxygen species was studied alone and following treatment with either 1 nM prazosin or 30 nM BMY 7378. Experiments were carried out as described in Methods. The results of a typical imaging study are presented along with a graphical summary of the statistical analysis of four independent experiments. Data were analyzed by a one-way ANOVA followed by post hoc testing. * Indicates a statistically significant difference from the untreated control.

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Journal of Molecular Signaling

ISSN: 1750-2187