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Table 4 Prediction results of PLS regression using all vital signaling metrics

From: Data-driven modeling of cellular stimulation, signaling and output response in RAW 264.7 cells

  G-CSF IL-1α IL-6 IL-10 MIP-1α RANTES TNFα
number of vital metrics 74 70 49 85 97 76 78
R 2 0.90 0.49 0.72 0.66 0.54 0.69 0.76
  1. For each cytokine, a PLS regression model using from 49 to 97 most informative (vital) signaling metrics was as predictive as the complete model that used all 231 metrics.