Figure 5

Effects of resveratrol and/or TRAIL on mitochondrial membrane potential (Δψ_m). (A), Resveratrol induces drop in Δψ_m. LNCaP cells were treated with or without resveratrol (20 μM) for 0–24 h. Cells were stained with JC1 dye, and Δψ_m was measured by a fluorometer as per manufacturer's instructions. (B), Interactive effects of resveratrol and TRAIL on Δψ_m. LNCaP cells were treated with resveratrol (20 μM) in the presence or absence of TRAIL (50 nM) for 1, 2, 8 and 16 h. Cells were stained with JC1 dye, and Δψ_m was measured.