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Figure 3 | Journal of Molecular Signaling

Figure 3

From: Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα12/13-Rho-Rac1 pathway

Figure 3

Effects of OGR1 over-expression on the activity of Rho family members in MCF7 cells. The activation levels of Rho (A), Rac1 (B) and Cdc42 (C) were examined by pull-down and Western blot analyses as described in Materials and Methods. Total Rho, Rac1, and Cdc42, as well as α-tubulin were analyzed in whole cell lysates. Representative results are from three independent experiments.

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