From: Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling
Gα 13residues in contact with p115-RH | myc-Gα12 QLNAAIRS mutant |
---|---|
Val98 | Q |
Asp101, Ala102 | R |
Lys105, Leu106 | S |
Thr127, Arg128 | V |
Phe168 | BB |
Arg200, Pro202, Lys204 | HH |
Gln226 | LL |
Arg230, Lys231, Phe234 | MM |
Met257 | |
Arg260 | RR |
Asn270 | SS |
Ile271, Glu273, Thr274, Ile275 | TT |
Asn278, Arg279, Val280 | UU |
Arg335 | DDD |