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Table 2 Pathological variables analysed in this study

From: Multiple biomarker tissue arrays: A computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway

PATHOLOGICAL

PATIENTS

RELATED MARKER

VARIABLES

NUMBER N = 80

 

Differentiation degree (Fuhrman Grade)

Well

15 (18.75%)

 

Moderate

45 (56,25%)

 

Poor

16 (20%)

 

Undifferentiated

4 (5%)

EGFR p = 0.081

Pelvis invasion

  

Yes

9 (11,25%)

EGFR p = 0.014

No

66 (82,5%)

 

Undetermined

5 6,25%)

 

Breaking capsule

  

Yes

12 (15%)

EGFR p = 0.008

No

64 (80%)

 

Undetermined

4 (5%)

 

Tumor depth

  

1

63 (78,75%)

 

2

4 (5%)

 

3

12 (15%)

EGFR p = 0.833

4

1 (1,25%)

 

Histology type

  

Clear cell

57 (71,25%)

EGFR p = 0.001

Papillary

6 (7,5%)

 

Chromophobe

15 (18,75%)

 

Undetermined

2 (2,5%)

 

Tumor localization

  

Right

40 (50%)

EGFR p = 0.275

Left

39 (48,75%)

 

Undetermined

1 (1,25%)

 

Veins invasion

  

Yes

9 (11,25%)

EGFR p = 0.475

No

67 (83,75%)

 

Undetermined

4 (5%)

 

Lymphatic vessels invasion

  

Yes

2 (2,5%)

EGFR p = 0.040

No

78 (97,5%)

 

Hilar invasion

  

Yes

6 (7,5%)

EGFR p = 0.029

No

68 (85%)

 

Undetermined

6 (7,5%)

 

Node involvement

  

0

19 (23,75%)

 

1–5

59 (73,75%)

 

>5

2 (2,5%)

EGFR p = 0.000