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Figure 1 | Journal of Molecular Signaling

Figure 1

From: Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells

Figure 1

Relative expression of various cancer stem cell markers in tumor remnants from APC Min +/- mice treated with dasatinib and/or curcumin as determined by RT-PCR. Tissue was procured from our previous study where Female Min mice (5 weeks; female C57BL/6J- APCMin +/- ) were treated with dasatinib (10 mg/kg body weight) and/or curcumin (250 mg/kg body weight). The treatment was given for five consecutive days per week for 4 weeks. At the end of respective treatments, the mice were euthanized and tumor remnants were obtained as described previously [30]. RNA isolated from the tissue was analyzed for expression of different CSCs specific markers.

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