Figure 4From: EGFR/Met association regulates EGFR TKI resistance in breast cancer Met phosphorylation occurs independent of ligand. SUM149 and SUM229 cells were treated with increasing concentrations of anti-HGF neutralizing antibody. The SUM149 cells were stimulated with 50 ng/ml HGF to induce Met phosphorylation. Whole cell lysates were immunoblotted with anti-phospho-Met.Back to article page