Figure 1
From: NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner
The effects of NSC109268 on the sensitivity of parental (2008) and cisplatin-resistant (2008/C13*) ovarian cancer cells to cisplatin. Cells were treated without (open circle) or with 2 μM NSC109268 (black circle) and varying concentrations of cisplatin for 72 h. Cell survival was determined by the MTT assay. The control values were based upon the results obtained in the absence of any drug but in the presence of vehicle or 2 μM NSC109268. Each value represents the mean ± SD of four determinants from a single microtiter plate. The results are representative of three independent experiments.