Figure 2From: TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling TLN-4601 reduces contact-independent proliferation in PDAC (A) and Ras-transformed immortalized duct derived cells (B). Cells were seeded into soft agar containing vehicle or various concentrations of TLN-4601. Bars represent the mean colonies per field, averaged from five fields per well, triplicate wells + SEM, n = 3 independent experiments. Insets are representative wells.Back to article page