Figure 1From: TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling TLN-4601 reduces contact-dependent proliferation in PDAC (A) and Ras-transformed immortalized duct derived cells (B). Cells were treated for 72 h with vehicle or various concentrations of TLN-4601 prior to the addition of the MTT reagent. Data represent the average of quadruplicate wells + SD of three independent experiments.Back to article page