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Figure 2 | Journal of Molecular Signaling

Figure 2

From: Molecular mechanism of regulation of OGG1: tuberin deficiency results in cytoplasmic redistribution of transcriptional factor NF-YA

Figure 2

Downregulation of tuberin expression in human renal epithelial cells results in decrease in NF-YA and OGG1 expression. A. Immunoblot analysis of tuberin, NF-YA and OGG1 in HEK 293 cells transfected with siRNA directed against TSC2 for 48 h. Actin was used as a loading control. B. Histograms represent means ± SE (n = 2). Significant differences from cells transfected with the TSC2-specific siRNA are indicated by **P < 0.01.

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