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Figure 5 | Journal of Molecular Signaling

Figure 5

From: Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition

Figure 5

Romidepsin more significantly alters the morphology of RIE-1 cells than that of NIH 3T3 cells. NIH 3T3 (A) or RIE-1 (B) cells stably expressing the indicated proteins were incubated in complete growth medium supplemented with DMSO (Vehicle), 5 nM romidepsin, or 10 μM U0126 for 48 h. Representative fields of cells were photographed under 10× magnification. Data shown are representative of at least two independent experiments.

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Journal of Molecular Signaling

ISSN: 1750-2187