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Figure 2 | Journal of Molecular Signaling

Figure 2

From: Romidepsin inhibits Ras-dependent growth transformation of NIH 3T3 fibroblasts and RIE-1 epithelial cells independently of Ras signaling inhibition

Figure 2

Romidepsin affects expression of cell cycle regulators. NIH 3T3 (A, C) or RIE-1 (B, D) cells stably expressing the indicated proteins were treated with DMSO (Vehicle) or the indicated concentration of romidepsin for 24 h. Cell lysates were analyzed by western blotting with antibodies to cyclin D1, p21, phospho-S608-Rb, and β-actin (loading control). Data shown are representative of at least two independent experiments.

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Journal of Molecular Signaling

ISSN: 1750-2187