Figure 4

Modulations in mRNA levels performed by TLDA for retinoic acid receptor-related genes ( RARα , RARβ , RAR γ, RXRα , and RXRβ ) occurring after BRCA2 -siRNA treatment and BRCA2 -siRNA with isoflavone exposure when compared to control cells corresponding to value 0, in MCF-7, MCF-10a, and MDA-MB-231 cell lines. Values are means ± SD for n = 3 assays. Statistical analysis were carried out by Student t-test (†, P < 0.01; *, P < 0.05).