Figure 2

Squared weighted VIP profile for RANTES. Ten PLS models were generated through 10-fold cross validation and then a weighted VIP score was computed as described in Materials and Methods to select the important signaling metrics. A segment plot was produced for each protein, with the radial length of each segment indicating the magnitude of the squared weighted VIP score for individual metrics. VIP scores greater than 1 (dashed circle) are classified as significant metrics. For example, here we see that the mean, maximum and AUC for JNKL/S activity are the most informative metrics for RANTES, while proteins such as EZR do not have predictive value under the conditions studied. see that the mean, maximum and AUC for JNKL/S activity are the most informative metrics for RANTES, while proteins such as EZR do not have predictive value under the conditions studied.