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Figure 5 | Journal of Molecular Signaling

Figure 5

From: Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis

Figure 5

Effects of curcumin on mitochondrial membrane potential. (A and B), Curcumin induces drop in mitochondrial membrane potential (Δψm). PC-3 and LNCaP cells were treated with or without curcumin (20 μM) for 0–24 h. Cells were stained with JC1 dye, and Δψm was measured by fluorometer as per manufacturer's instructions. (C and D), Interactive effects of curcumin and TRAIL on Δψm. PC-3 and LNCaP cells were treated with or without curcumin (20 μM) in the presence or absence of TRAIL for 0, 8, or 16 h. Cells were stained with JC1 dye to measure Δψm. * = significantly different from respective control (P < 0.05).

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Journal of Molecular Signaling

ISSN: 1750-2187